https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Anti-Leukaemic Activity of Rilpivirine Is Mediated by Aurora A Kinase Inhibition https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51640 Wed 28 Feb 2024 15:44:33 AEDT ]]> Neoadjuvant Treatment with HER2-Targeted Therapies in HER2-Positive Breast Cancer: A Systematic Review and Network Meta-Analysis https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:48928 Wed 19 Apr 2023 15:08:55 AEST ]]> Examining the expression of nucleotide excision repair genes in melanoma tumours https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27892 Wed 11 Apr 2018 16:44:14 AEST ]]> Omalizumab treatment response in a population with severe allergic asthma and overlapping COPD https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33179 1 < 80% predicted to those with an FEV₁ > 80% predicted after bronchodilator use. In the population with an FEV₁< 80%, analysis was further stratified based on smoking history. Results: Omalizumab treatment markedly improved asthma control and health-related quality of life in all populations assessed based on the Asthma Control Questionnaire and Asthma Quality of Life Questionnaire scores. Omalizumab treatment did not improve lung function (FEV₁, FVC, or FEV₁/FVC ratio) in populations that were enriched for asthma-COPD overlap (diagnosis of COPD or FEV₁ < 80%/ever smokers). Conclusions: Our study suggests that omalizumab improves asthma control and health-related quality of life in individuals with severe allergic asthma and overlapping COPD. These findings provide real-world efficacy data for this patient population and suggest that omalizumab is useful in the management of severe asthma with COPD overlap.]]> Wed 04 Sep 2019 09:48:23 AEST ]]> Targeted therapeutics for severe refractory asthma: Monoclonal antibodies https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:50315 Tue 18 Jul 2023 12:37:57 AEST ]]> Real-World Outcomes in Patients With Brain Metastases Secondary to HER2-Positive Breast Cancer: An Australian Multi-centre Registry-based Study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52763 Tue 14 Nov 2023 15:23:12 AEDT ]]> Severe asthma: current management, targeted therapies and future directions-a roundtable report https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33751 Tue 08 Jan 2019 15:37:34 AEDT ]]> Albumin hybrid nanoparticles loaded with tyrosine kinase A inhibitor GNF-5837 for targeted inhibition of breast cancer cell growth and invasion https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:25752 Thu 28 Oct 2021 13:04:14 AEDT ]]> Severe asthma assessment, management and the organisation of care in Australia and New Zealand: expert forum roundtable meetings https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:39023 Thu 21 Apr 2022 09:51:00 AEST ]]> Targeting the TSH receptor in thyroid cancer https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32094 Thu 17 Mar 2022 14:40:51 AEDT ]]> Metastatic melanoma treatment: combining old and new therapies https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29594 Thu 03 Feb 2022 12:21:03 AEDT ]]> Current strategies in overcoming resistance of cancer cells to apaptosis melanoma as a model https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:3484 Sat 24 Mar 2018 10:57:58 AEDT ]]> Current strategies in overcoming resistance of cancer cells to apaptosis melanoma as a model https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:3483 Sat 24 Mar 2018 10:57:58 AEDT ]]> Extracranial oligometastatic renal cell carcinoma: current management and future directions https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20621 Sat 24 Mar 2018 07:55:45 AEDT ]]> Asthma 2014: from monoclonals to the microbiome https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:22281 Sat 24 Mar 2018 07:17:42 AEDT ]]> Multifunctional nanomedicines based on albumin for targeted breast cancer therapy https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27891 Mon 23 Sep 2019 10:12:42 AEST ]]> Metastatic acral melanoma treatment outcomes: A systematic review and meta-analysis https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:48478 Mon 20 Mar 2023 09:17:54 AEDT ]]> Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:50946 Mon 14 Aug 2023 14:01:12 AEST ]]> Moving towards a Treatable Traits model of care for the management of obstructive airways diseases https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:48632 Fri 24 Mar 2023 10:57:01 AEDT ]]>